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B-Cell-Intrinsic Hepatitis C Virus Expression Leads to B-Cell-Lymphomagenesis and Induction of NF-κB Signalling

Hepatitis C virus (HCV) infection leads to the development of hepatic diseases, as well as extrahepatic disorders such as B-cell non-Hodgkin's lymphoma (B-NHL). To reveal the molecular signalling pathways responsible for HCV-associated B-NHL development, we utilised transgenic (Tg) mice that ex...

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Detalles Bibliográficos
Autores principales: Kasama, Yuri, Mizukami, Takuo, Kusunoki, Hideki, Peveling-Oberhag, Jan, Nishito, Yasumasa, Ozawa, Makoto, Kohara, Michinori, Mizuochi, Toshiaki, Tsukiyama-Kohara, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961254/
https://www.ncbi.nlm.nih.gov/pubmed/24651473
http://dx.doi.org/10.1371/journal.pone.0091373