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Nested PCR for mtDNA-4977-bp deletion and comet assay for DNA damage - a combined method for radiosensitivity evaluation of tumor cells

To identify an effective method of evaluating the radiosensitivity of human tumor cell lines in vitro, the present study adopted mtDNA-4977-bp deletion coupled with comet assay. The three human tumor cell lines applied were HepG(2), EC-9706 and MCF-7. The surviving fraction (SF), ratio of the mtDNA-...

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Detalles Bibliográficos
Autores principales: LI, JIANGUO, WANG, YAN, DU, LIQING, XU, CHANG, CAO, JIA, WANG, QIN, LIU, QIANG, FAN, FEIYUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961259/
https://www.ncbi.nlm.nih.gov/pubmed/24944673
http://dx.doi.org/10.3892/ol.2014.1819