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Tissue Specific DNA Methylation in Normal Human Breast Epithelium and in Breast Cancer

Cancer is a heterogeneous and tissue-specific disease. Thus, the tissue of origin reflects on the natural history of the disease and dictates the therapeutic approach. It is suggested that tissue differentiation, mediated mostly by epigenetic modifications, could guide tissue-specific susceptibility...

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Detalles Bibliográficos
Autores principales: Avraham, Ayelet, Cho, Sean Soonweng, Uhlmann, Ronit, Polak, Mia Leonov, Sandbank, Judith, Karni, Tami, Pappo, Itzhak, Halperin, Ruvit, Vaknin, Zvi, Sella, Avishay, Sukumar, Saraswati, Evron, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961270/
https://www.ncbi.nlm.nih.gov/pubmed/24651077
http://dx.doi.org/10.1371/journal.pone.0091805