Microsatellite Stable Colorectal Cancers Stratified by the BRAF V600E Mutation Show Distinct Patterns of Chromosomal Instability

The BRAF (V600E) mutation in colorectal cancers that are microsatellite stable (MSS) confers a poor patient prognosis, whereas BRAF mutant microsatellite-unstable (MSI) colorectal cancers have an excellent prognosis. BRAF wild type cancers are typically MSS and display chromosomal instability (CIN)....

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Detalles Bibliográficos
Autores principales: Bond, Catherine E., Nancarrow, Derek J., Wockner, Leesa F., Wallace, Leanne, Montgomery, Grant W., Leggett, Barbara A., Whitehall, Vicki L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961279/
https://www.ncbi.nlm.nih.gov/pubmed/24651849
http://dx.doi.org/10.1371/journal.pone.0091739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961279/
https://www.ncbi.nlm.nih.gov/pubmed/24651849
http://dx.doi.org/10.1371/journal.pone.0091739

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