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Efficient synthesis of chloro-derivatives of sialosyllactosylceramide, and their enhanced inhibitory effect on epidermal growth factor receptor activation

Glycosphingolipids are components of essentially all mammalian cell membranes and are involved in a variety of significant cellular functions, including proliferation, adhesion, motility and differentiation. Sialosyllactosylceramide (GM3) is known to inhibit the activation of epidermal growth factor...

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Detalles Bibliográficos
Autores principales: KAWASHIMA, NAGAKO, QU, HUANHUAN, LOBATON, MARLIN, ZHU, ZHENYUAN, SOLLOGOUB, MATTHIEU, CAVENEE, WEBSTER K., HANDA, KAZUKO, HAKOMORI, SEN-ITIROH, ZHANG, YONGMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961331/
https://www.ncbi.nlm.nih.gov/pubmed/24944646
http://dx.doi.org/10.3892/ol.2014.1887