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Efficient synthesis of chloro-derivatives of sialosyllactosylceramide, and their enhanced inhibitory effect on epidermal growth factor receptor activation
Glycosphingolipids are components of essentially all mammalian cell membranes and are involved in a variety of significant cellular functions, including proliferation, adhesion, motility and differentiation. Sialosyllactosylceramide (GM3) is known to inhibit the activation of epidermal growth factor...
Autores principales: | KAWASHIMA, NAGAKO, QU, HUANHUAN, LOBATON, MARLIN, ZHU, ZHENYUAN, SOLLOGOUB, MATTHIEU, CAVENEE, WEBSTER K., HANDA, KAZUKO, HAKOMORI, SEN-ITIROH, ZHANG, YONGMIN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961331/ https://www.ncbi.nlm.nih.gov/pubmed/24944646 http://dx.doi.org/10.3892/ol.2014.1887 |
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