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HMGB1-Promoted and TLR2/4-Dependent NK Cell Maturation and Activation Take Part in Rotavirus-Induced Murine Biliary Atresia

Recent studies show that NK cells play important roles in murine biliary atresia (BA), and a temporary immunological gap exists in this disease. In this study, we found high-mobility group box-1 (HMGB1) and TLRs were overexpressed in human and rotavirus-induced murine BA. The overexpressed HMGB1 rel...

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Detalles Bibliográficos
Autores principales: Qiu, Yinrong, Yang, Jixin, Wang, Wenmei, Zhao, Wentao, Peng, Fei, Xiang, Ying, Chen, Gang, Chen, Tao, Chai, Chengwei, Zheng, Shuaiyu, Watkins, Daniel J., Feng, Jiexiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961347/
https://www.ncbi.nlm.nih.gov/pubmed/24651485
http://dx.doi.org/10.1371/journal.ppat.1004011