Activation of HIV-1 from Latent Infection via Synergy of RUNX1 Inhibitor Ro5-3335 and SAHA

A major barrier to the elimination of HIV-1 infection is the presence of a pool of long-lived, latently infected CD4+ memory T-cells. The search for treatments to re-activate latent HIV to aid in clearance is hindered by the incomplete understanding of the mechanisms that lead to transcriptional sil...

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Detalles Bibliográficos
Autores principales: Klase, Zachary, Yedavalli, Venkat S. R. K., Houzet, Laurent, Perkins, Molly, Maldarelli, Frank, Brenchley, Jason, Strebel, Klaus, Liu, Paul, Jeang, Kuan-Teh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961356/
https://www.ncbi.nlm.nih.gov/pubmed/24651404
http://dx.doi.org/10.1371/journal.ppat.1003997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961356/
https://www.ncbi.nlm.nih.gov/pubmed/24651404
http://dx.doi.org/10.1371/journal.ppat.1003997

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