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Analysis of Multiple Association Studies Provides Evidence of an Expression QTL Hub in Gene-Gene Interaction Network Affecting HDL Cholesterol Levels

Epistasis has been suggested to underlie part of the missing heritability in genome-wide association studies. In this study, we first report an analysis of gene-gene interactions affecting HDL cholesterol (HDL-C) levels in a candidate gene study of 2,091 individuals with mixed dyslipidemia from a cl...

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Detalles Bibliográficos
Autores principales: Ma, Li, Ballantyne, Christie, Brautbar, Ariel, Keinan, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961362/
https://www.ncbi.nlm.nih.gov/pubmed/24651390
http://dx.doi.org/10.1371/journal.pone.0092469