BRCA1 promoter hypermethylation in sporadic epithelial ovarian carcinoma: Association with low expression of BRCA1, improved survival and co-expression of DNA methyltransferases

The breast cancer susceptibility gene 1 (BRCA1) inactivation in sporadic epithelial ovarian carcinoma (EOC) is common and low BRCA1 expression is associated with promoter hypermethylation. The clinical validation of BRCA1 methylation as a prognostic marker in EOC remains unresolved. The aim of the p...

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Detalles Bibliográficos
Autores principales: BAI, XUEFENG, FU, YINGZI, XUE, HUI, GUO, KEJUN, SONG, ZHIGUO, YU, ZHAOJIN, JIA, TIANHONG, YAN, YUANYUAN, ZHAO, LIN, MI, XIAOYI, WANG, ENHUA, ZHENG, ZHIHONG, ZHAO, HAISHAN, YAO, WEIFAN, WEI, MINJIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961372/
https://www.ncbi.nlm.nih.gov/pubmed/24944674
http://dx.doi.org/10.3892/ol.2014.1878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961372/
https://www.ncbi.nlm.nih.gov/pubmed/24944674
http://dx.doi.org/10.3892/ol.2014.1878

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