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Characterisation of Genetic Variation in ST8SIA2 and Its Interaction Region in NCAM1 in Patients with Bipolar Disorder
Alpha-2,8-sialyltransferase 2 (ST8SIA2) is an enzyme responsible for the transfer of polysialic acid (PSA) to glycoproteins, principally the neuronal cell adhesion molecule (NCAM1), and is involved in neuronal plasticity. Variants within ST8SIA2 have previously shown association with bipolar disorde...
Autores principales: | Shaw, Alex D., Tiwari, Yash, Kaplan, Warren, Heath, Anna, Mitchell, Philip B., Schofield, Peter R., Fullerton, Janice M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961385/ https://www.ncbi.nlm.nih.gov/pubmed/24651862 http://dx.doi.org/10.1371/journal.pone.0092556 |
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