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Twist2 contributes to cisplatin-resistance of ovarian cancer through the AKT/GSK-3β signaling pathway
Cisplatin is regularly used in the treatment of ovarian cancer. However, the drug only provides a modest survival advantage, primarily due to chemoresistance and the upregulation of antiapoptotic machineries in ovarian cancer cells. Therefore, targeting the mechanisms responsible for cisplatin resis...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961411/ https://www.ncbi.nlm.nih.gov/pubmed/24944676 http://dx.doi.org/10.3892/ol.2014.1816 |