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hSulf-1 inhibits cell proliferation and migration and promotes apoptosis by suppressing stat3 signaling in hepatocellular carcinoma

Human sulfatase-1 (hSulf-1) has been shown to desulfate cellular heparin sulfate proteoglycans and modulate several growth factors and cytokines. However, hSulf-1 has not been previously shown to mediate the signal transducer and activator of transcription 3 (stat3) signaling pathway, which is known...

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Detalles Bibliográficos
Autores principales: LIU, LING, DING, FENG, CHEN, JIWEI, WANG, BOYONG, LIU, ZHISU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961425/
https://www.ncbi.nlm.nih.gov/pubmed/24944651
http://dx.doi.org/10.3892/ol.2014.1848