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Histone Deacetylase Inhibitors Improve the Replication of Oncolytic Herpes Simplex Virus in Breast Cancer Cells

New therapies are needed for metastatic breast cancer patients. Oncolytic herpes simplex virus (oHSV) is an exciting therapy being developed for use against aggressive tumors and established metastases. Although oHSV have been demonstrated safe in clinical trials, a lack of sufficient potency has sl...

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Detalles Bibliográficos
Autores principales: Cody, James J., Markert, James M., Hurst, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961437/
https://www.ncbi.nlm.nih.gov/pubmed/24651853
http://dx.doi.org/10.1371/journal.pone.0092919