Hydroxychloroquine facilitates autophagosome formation but not degradation to suppress the proliferation of cervical cancer SiHa cells

Hydroxychloroquine (HCQ), the hydroxylated analog of chloroquine, is an antimalarial lysomotropic agent that inhibits autophagy due to lysosomal acidification, and subsequently blocks the fusion of autophagosomes with lysosomes which leads to the accumulation of autophagosomes that may accelerate tu...

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Detalles Bibliográficos
Autores principales: LIU, QINGSONG, LUO, XIONG YAN, JIANG, HONG, YANG, MING-HUI, YUAN, GUO-HUA, TANG, ZHONG, WANG, HE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961458/
https://www.ncbi.nlm.nih.gov/pubmed/24944668
http://dx.doi.org/10.3892/ol.2014.1879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961458/
https://www.ncbi.nlm.nih.gov/pubmed/24944668
http://dx.doi.org/10.3892/ol.2014.1879

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