A novel pathway links telomeres to NK-cell activity: Implications for immunotherapy

Here, we describe a model in which telomeric repeat-binding factor 2 (TERF2) can control tumorigenesis not only via cancer cell-intrinsic mechanisms but also via non-cancer cell autonomous pathways. Indeed, we have recently shown that TERF2 regulates tissue homeostasis as it promotes the elimination...

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Detalles Bibliográficos
Autores principales: Cherfils-Vicini, Julien, Zizza, Pasquale, Gilson, Eric, Biroccio, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961481/
https://www.ncbi.nlm.nih.gov/pubmed/24701373
http://dx.doi.org/10.4161/onci.27358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961481/
https://www.ncbi.nlm.nih.gov/pubmed/24701373
http://dx.doi.org/10.4161/onci.27358

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