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SECTM1 Produced by Tumor Cells Attracts Human Monocytes Via CD7-mediated Activation of the PI3K Pathway

Tumor-associated macrophages (TAMs) play essential roles in tumor progression and metastasis. Tumor cells recruit myeloid progenitors and monocytes to the tumor site, where they differentiate into TAMs; however, this process is not well studied in humans. Here we show that human CD7, a T cell and NK...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Ge, Yingbin, Xiao, Min, Lopez-Coral, Alfonso, Li, Ling, Roesch, Alexander, Huang, Catherine, Alexander, Peter, Vogt, Thomas, Xu, Xiaowei, Hwang, Wei-Ting, Lieu, Melissa, Belser, Eric, Liu, Rui, Somasundaram, Rajasekharan, Herlyn, Meenhard, Kaufman, Russel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961532/
https://www.ncbi.nlm.nih.gov/pubmed/24157461
http://dx.doi.org/10.1038/jid.2013.437