Additive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility

The phosphatidylinositol-3-kinase/Akt pathway and receptor tyrosine kinases regulate many tumorigenesis related cellular processes including cell metabolism, cell survival, cell motility, and angiogenesis. Anaplastic thyroid carcinoma (ATC) is a rare type of thyroid cancer with no effective systemic...

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Detalles Bibliográficos
Autores principales: Che, Huan-yong, Guo, Hang-yuan, Si, Xu-wei, You, Qiao-ying, Lou, Wei-ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961587/
https://www.ncbi.nlm.nih.gov/pubmed/24665203
http://dx.doi.org/10.2147/OTT.S57324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961587/
https://www.ncbi.nlm.nih.gov/pubmed/24665203
http://dx.doi.org/10.2147/OTT.S57324

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