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Additive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility

The phosphatidylinositol-3-kinase/Akt pathway and receptor tyrosine kinases regulate many tumorigenesis related cellular processes including cell metabolism, cell survival, cell motility, and angiogenesis. Anaplastic thyroid carcinoma (ATC) is a rare type of thyroid cancer with no effective systemic...

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Detalles Bibliográficos
Autores principales:	Che, Huan-yong, Guo, Hang-yuan, Si, Xu-wei, You, Qiao-ying, Lou, Wei-ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961587/ https://www.ncbi.nlm.nih.gov/pubmed/24665203 http://dx.doi.org/10.2147/OTT.S57324

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