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Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Luseogliflozin Dosing in Healthy Japanese Males: A Randomized, Single-Blind, Placebo-Controlled Trial

INTRODUCTION: Luseogliflozin, a sodium glucose cotransporter 2 inhibitor, inhibits reabsorption of glucose in the proximal renal tubule. It was developed for the treatment of type 2 diabetes mellitus. METHODS: For this first human study of luseogliflozin, randomized, single-blind, placebo-controlled...

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Detalles Bibliográficos
Autores principales: Sasaki, Takashi, Seino, Yutaka, Fukatsu, Atsushi, Sakai, Soichi, Samukawa, Yoshishige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961596/
https://www.ncbi.nlm.nih.gov/pubmed/24535625
http://dx.doi.org/10.1007/s12325-014-0102-3