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Methyllysine Reader Plant Homeodomain (PHD) Finger Protein 20-like 1 (PHF20L1) Antagonizes DNA (Cytosine-5) Methyltransferase 1 (DNMT1) Proteasomal Degradation

Inheritance of DNA cytosine methylation pattern during successive cell division is mediated by maintenance DNA (cytosine-5) methyltransferase 1 (DNMT1). Lysine 142 of DNMT1 is methylated by the SET domain containing lysine methyltransferase 7 (SET7), leading to its degradation by proteasome. Here we...

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Detalles Bibliográficos
Autores principales: Estève, Pierre-Olivier, Terragni, Jolyon, Deepti, Kanneganti, Chin, Hang Gyeong, Dai, Nan, Espejo, Alexsandra, Corrêa, Ivan R., Bedford, Mark T., Pradhan, Sriharsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961655/
https://www.ncbi.nlm.nih.gov/pubmed/24492612
http://dx.doi.org/10.1074/jbc.M113.525279