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Novel Ubiquitin-derived High Affinity Binding Proteins with Tumor Targeting Properties

Targeting effector molecules to tumor cells is a promising mode of action for cancer therapy and diagnostics. Binding proteins with high affinity and specificity for a tumor target that carry effector molecules such as toxins, cytokines, or radiolabels to their intended site of action are required f...

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Detalles Bibliográficos
Autores principales: Lorey, Susan, Fiedler, Erik, Kunert, Anja, Nerkamp, Jörg, Lange, Christian, Fiedler, Markus, Bosse-Doenecke, Eva, Meysing, Maren, Gloser, Manja, Rundfeldt, Chris, Rauchhaus, Una, Hänssgen, Ilka, Göttler, Thomas, Steuernagel, Arnd, Fiedler, Ulrike, Haupts, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961674/
https://www.ncbi.nlm.nih.gov/pubmed/24474690
http://dx.doi.org/10.1074/jbc.M113.519884