Origin of the Proton-transfer Step in the Cofactor-free (1H)-3-Hydroxy-4-oxoquinaldine 2,4-Dioxygenase: EFFECT OF THE BASICITY OF AN ACTIVE SITE HIS RESIDUE

Dioxygenases catalyze a diverse range of chemical reactions that involve the incorporation of oxygen into a substrate and typically use a transition metal or organic cofactor for reaction. Bacterial (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase (HOD) belongs to a class of oxygenases able to catalyz...

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Detalles Bibliográficos
Autores principales: Hernandez-Ortega, Aitor, Quesne, Matthew G., Bui, Soi, Heuts, Dominic P. H. M., Steiner, Roberto A., Heyes, Derren J., de Visser, Sam P., Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961685/
https://www.ncbi.nlm.nih.gov/pubmed/24482238
http://dx.doi.org/10.1074/jbc.M113.543033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961685/
https://www.ncbi.nlm.nih.gov/pubmed/24482238
http://dx.doi.org/10.1074/jbc.M113.543033

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