Wnt Signaling Induces Epithelial-Mesenchymal Transition with Proliferation in ARPE-19 Cells upon Loss of Contact Inhibition

Proliferation and epithelial-mesenchymal transition (EMT) of the retinal pigment epithelium (RPE) are hallmarks of proliferative vitreoretinopathy. This study aims at clarifying the role of growth factors, i.e. epidermal growth factor (EGF), fibroblast growth factor-2 (FGF-2), and transforming growt...

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Detalles Bibliográficos
Autores principales: Chen, Hung-Chi, Zhu, Ying-Ting, Chen, Szu-Yu, Tseng, Scheffer C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961713/
https://www.ncbi.nlm.nih.gov/pubmed/22391957
http://dx.doi.org/10.1038/labinvest.2011.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961713/
https://www.ncbi.nlm.nih.gov/pubmed/22391957
http://dx.doi.org/10.1038/labinvest.2011.201

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