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Structure and Permeability of Ion-channels by Integrated AFM and Waveguide TIRF Microscopy
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate. Solid substrate prevents molecular transport through ion channels thus hindering any direct...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961736/ https://www.ncbi.nlm.nih.gov/pubmed/24651823 http://dx.doi.org/10.1038/srep04424 |