Structure and Permeability of Ion-channels by Integrated AFM and Waveguide TIRF Microscopy

Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate. Solid substrate prevents molecular transport through ion channels thus hindering any direct...

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Detalles Bibliográficos
Autores principales: Ramachandran, Srinivasan, Arce, Fernando Teran, Patel, Nirav R., Quist, Arjan P., Cohen, Daniel A., Lal, Ratnesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961736/
https://www.ncbi.nlm.nih.gov/pubmed/24651823
http://dx.doi.org/10.1038/srep04424

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