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Aberrant p16INK4A methylation: Relation to viral related chronic liver disease and hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer related deaths. Several studies have shown that the tumor suppressor gene p16INK4A is frequently downregulated by aberrant methylation of the 5’-cytosine-phosphog...

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Detalles Bibliográficos
Autores principales: El-Mougy, Fatma A., Youssef, Mohammed M., Omran, Dalia A., Sharaf, Sahar A., El-Sayed, Hany H., Rabie, Walaa A., Mohamed, Elghobary A., Elghobary, Hany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961859/
https://www.ncbi.nlm.nih.gov/pubmed/24665436
http://dx.doi.org/10.4103/2278-330X.126498