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Quantitative assessment of invasive mena isoforms (Mena(calc)) as an independent prognostic marker in breast cancer

INTRODUCTION: Mena, an Ena/VASP protein family member, is a key actin regulatory protein. Mena is up-regulated in breast cancers and promotes invasion and motility of tumor cells. Mena has multiple splice variants, including Mena invasive (Mena(INV)) and Mena11a, which are expressed in invasive or n...

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Detalles Bibliográficos
Autores principales: Agarwal, Seema, Gertler, Frank B, Balsamo, Michele, Condeelis, John S, Camp, Robert L, Xue, Xiaonan, Lin, Juan, Rohan, Thomas E, Rimm, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962029/
https://www.ncbi.nlm.nih.gov/pubmed/22971274
http://dx.doi.org/10.1186/bcr3318