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Computational enzyme design approaches with significant biological outcomes: progress and challenges
Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of enzyme-based practical applications and that of naturally occurring enzymes. Multiple experimental approaches have been applied to generate nearly all possible mutations of target enzymes, allowing th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962085/ https://www.ncbi.nlm.nih.gov/pubmed/24688648 http://dx.doi.org/10.5936/csbj.201209007 |