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Computational enzyme design approaches with significant biological outcomes: progress and challenges

Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of enzyme-based practical applications and that of naturally occurring enzymes. Multiple experimental approaches have been applied to generate nearly all possible mutations of target enzymes, allowing th...

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Detalles Bibliográficos
Autores principales: Li, Xiaoman, Zhang, Ziding, Song, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962085/
https://www.ncbi.nlm.nih.gov/pubmed/24688648
http://dx.doi.org/10.5936/csbj.201209007