The Role of INDY in Metabolic Regulation

Reduced expression of the Indy (I'm Not Dead Yet) gene in D. melanogaster and C. elegans extends longevity. Indy and its mammalian homolog mINDY (Slc13a5, NaCT) are transporters of TCA cycle intermediates, mainly handling the uptake of citrate via the plasma membrane into the cytosol. Deletion...

Descripción completa

Detalles Bibliográficos
Autores principales: Willmes, Diana M, Birkenfeld, Andreas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962103/
https://www.ncbi.nlm.nih.gov/pubmed/24688728
http://dx.doi.org/10.5936/csbj.201303020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962103/
https://www.ncbi.nlm.nih.gov/pubmed/24688728
http://dx.doi.org/10.5936/csbj.201303020

Ejemplares similares