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The Role of INDY in Metabolic Regulation
Reduced expression of the Indy (I'm Not Dead Yet) gene in D. melanogaster and C. elegans extends longevity. Indy and its mammalian homolog mINDY (Slc13a5, NaCT) are transporters of TCA cycle intermediates, mainly handling the uptake of citrate via the plasma membrane into the cytosol. Deletion...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962103/ https://www.ncbi.nlm.nih.gov/pubmed/24688728 http://dx.doi.org/10.5936/csbj.201303020 |