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The role of Lipoxin A4 in Cystic Fibrosis Lung Disease

In Cystic Fibrosis (CF), mutations of the CFTR gene result in defective Cl(−) secretion and Na(+) hyperabsorption by epithelia which leads to airway lumen dehydration and mucus plugging and favours chronic bacterial colonization, persistent inflammation and progressive lung destruction. Beyond this...

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Detalles Bibliográficos
Autores principales: Urbach, Valérie, Higgins, Gerard, Buchanan, Paul, Ringholz, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962119/
https://www.ncbi.nlm.nih.gov/pubmed/24688726
http://dx.doi.org/10.5936/csbj.201303018