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The role of Lipoxin A4 in Cystic Fibrosis Lung Disease
In Cystic Fibrosis (CF), mutations of the CFTR gene result in defective Cl(−) secretion and Na(+) hyperabsorption by epithelia which leads to airway lumen dehydration and mucus plugging and favours chronic bacterial colonization, persistent inflammation and progressive lung destruction. Beyond this...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962119/ https://www.ncbi.nlm.nih.gov/pubmed/24688726 http://dx.doi.org/10.5936/csbj.201303018 |