Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulation by lipid IVa

There is literature evidence gathered throughout the last two decades reflecting unexpected species differences concerning the immune response to lipid IVa which provides the opportunity to gain more detailed insight by the molecular modeling approach described in this study. Lipid IVa is a tetra-ac...

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Detalles Bibliográficos
Autores principales: Scior, Thomas, Alexander, Christian, Zaehringer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:
Mini Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962135/
https://www.ncbi.nlm.nih.gov/pubmed/24688705
http://dx.doi.org/10.5936/csbj.201302012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962135/
https://www.ncbi.nlm.nih.gov/pubmed/24688705
http://dx.doi.org/10.5936/csbj.201302012

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