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Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites

Nicotinamide adenine dinucleotide (NAD(+)) is a coenzyme for hydride transfer reactions and a substrate for sirtuins and other NAD(+)-consuming enzymes. The abundance of NAD (+), NAD(+) biosynthetic intermediates, and related nucleotides reflects the metabolic state of cells and tissues. High perfor...

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Detalles Bibliográficos
Autores principales: Trammell, Samuel AJ, Brenner, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962138/
https://www.ncbi.nlm.nih.gov/pubmed/24688693
http://dx.doi.org/10.5936/csbj.201301012