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Computational tools for rational protein engineering of aldolases

In this mini-review we describe the different strategies for rational protein engineering and summarize the computational tools available. Computational tools can either be used to design focused libraries, to predict sequence-function relationships or for structure-based molecular modelling. This a...

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Detalles Bibliográficos
Autores principales: Widmann, Michael, Pleiss, Jürgen, Samland, Anne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962226/
https://www.ncbi.nlm.nih.gov/pubmed/24688657
http://dx.doi.org/10.5936/csbj.201209016