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Exposure to phages has little impact on the evolution of bacterial antibiotic resistance on drug concentration gradients
The use of phages for treating bacterial pathogens has recently been advocated as an alternative to antibiotic therapy. Here, we test a hypothesis that bacteria treated with phages may show more limited evolution of antibiotic resistance as the fitness costs of resistance to phages may add to those...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962299/ https://www.ncbi.nlm.nih.gov/pubmed/24665341 http://dx.doi.org/10.1111/eva.12136 |