Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells

AIMS: Genistein, an isoflavone derivative found in soy, is known as a promising treatment for rheumatoid arthritis (RA). However, the detailed molecular mechanism of genistein in suppression of proinflammatory cytokine production remains ambiguous. The aim of this work was to evaluate the signal pat...

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Detalles Bibliográficos
Autores principales: Li, Jinchao, Li, Jun, Yue, Ye, Hu, Yiping, Cheng, Wenxiang, Liu, Ruoxi, Pan, Xiaohua, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962316/
https://www.ncbi.nlm.nih.gov/pubmed/24669186
http://dx.doi.org/10.2147/DDDT.S52354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962316/
https://www.ncbi.nlm.nih.gov/pubmed/24669186
http://dx.doi.org/10.2147/DDDT.S52354

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