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Impaired Fear Extinction as Displayed by Serotonin Transporter Knockout Rats Housed in Open Cages Is Disrupted by IVC Cage Housing

Anxiety disorders are influenced by both environmental and genetic factors. A well-known example for gene x environment interactions in psychiatry is the low activity (s) allelic variant of the serotonin transporter (5-HTT) promoter polymorphism (5-HTTLPR) that in the context of stress increases ris...

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Detalles Bibliográficos
Autores principales: Shan, Ling, Schipper, Pieter, Nonkes, Lourens J. P., Homberg, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962352/
https://www.ncbi.nlm.nih.gov/pubmed/24658187
http://dx.doi.org/10.1371/journal.pone.0091472