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Human α-Defensin Expression Is Not Dependent on CCAAT/Enhancer Binding Protein-ε in a Murine Model

Specific granule deficiency (SGD) is a rare congenital disorder characterized by recurrent infections. The disease is caused by inactivating mutations of the CCAAT/enhancer binding protein-ε (C/EBP-ε) gene. As a consequence, specific and gelatinase granules lack most matrix proteins. Furthermore, az...

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Detalles Bibliográficos
Autores principales: Glenthøj, Andreas, Dahl, Sara, Larsen, Maria T., Cowland, Jack B., Borregaard, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962403/
https://www.ncbi.nlm.nih.gov/pubmed/24658030
http://dx.doi.org/10.1371/journal.pone.0092471