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Either Non-Homologous Ends Joining or Homologous Recombination Is Required to Repair Double-Strand Breaks in the Genome of Macrophage-Internalized Mycobacterium tuberculosis

The intracellular pathogen Mycobacterium tuberculosis (Mtb) is constantly exposed to a multitude of hostile conditions and is confronted by a variety of potentially DNA-damaging assaults in vivo, primarily from host-generated antimicrobial toxic radicals. Exposure to reactive nitrogen species and/or...

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Detalles Bibliográficos
Autores principales: Brzostek, Anna, Szulc, Izabela, Klink, Magdalena, Brzezinska, Marta, Sulowska, Zofia, Dziadek, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962454/
https://www.ncbi.nlm.nih.gov/pubmed/24658131
http://dx.doi.org/10.1371/journal.pone.0092799