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Metabolic and Environmental Conditions Determine Nuclear Genomic Instability in Budding Yeast Lacking Mitochondrial DNA

Mitochondrial dysfunctions are an internal cause of nuclear genome instability. Because mitochondria are key regulators of cellular metabolism, we have investigated a potential link between external growth conditions and nuclear chromosome instability in cells with mitochondrial defects. Using Sacch...

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Detalles Bibliográficos
Autores principales: Dirick, Léon, Bendris, Walid, Loubiere, Vincent, Gostan, Thierry, Gueydon, Elisabeth, Schwob, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962481/
https://www.ncbi.nlm.nih.gov/pubmed/24374640
http://dx.doi.org/10.1534/g3.113.010108