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The anticancer effects of HDAC inhibitors require the immune system

Histone deacetylase inhibitors (HDACis) are known to exert immunomodulatory effects. We have recently demonstrated that the therapeutic efficacy of HDACis against aggressive B-cell lymphoma and colon carcinoma relies on a functional immune system, in particular on the production of interferon γ (IFN...

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Detalles Bibliográficos
Autores principales: West, Alison C, Smyth, Mark J, Johnstone, Ricky W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962507/
https://www.ncbi.nlm.nih.gov/pubmed/24701376
http://dx.doi.org/10.4161/onci.27414