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Use of monitoring levels of soluble forms of cytokeratin 18 in the urine of patients with superficial bladder cancer following intravesical Ad-IFNα/Syn3 treatment in a Phase l study
A phase l study using intravesical Ad-IFNα/Syn3 for patients with BCG resistant superficial bladder cancer showed a complete remission (CR) of 43% at 90 days after treatment with high levels of IFNα being produced. Ad-IFNα kills bladder cancer cells by two apoptotic and one necrotic mechanism that c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962717/ https://www.ncbi.nlm.nih.gov/pubmed/24503570 http://dx.doi.org/10.1038/cgt.2014.1 |