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Sphingosine Kinases/Sphingosine-1-Phosphate and Death Signalling in APP-Transfected Cells
It has been postulated that disturbances in the sphingolipid metabolism play a key role in the pathogenesis of Alzheimer’s disease (AD). An alteration in sphingosine kinases 1, 2 (SphK1/2) and sphingosine-1-phosphate (S1P) was recently reported in AD. However, the effect of AD-related amyloid beta (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962740/ https://www.ncbi.nlm.nih.gov/pubmed/24452756 http://dx.doi.org/10.1007/s11064-014-1240-3 |