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Sphingosine Kinases/Sphingosine-1-Phosphate and Death Signalling in APP-Transfected Cells

It has been postulated that disturbances in the sphingolipid metabolism play a key role in the pathogenesis of Alzheimer’s disease (AD). An alteration in sphingosine kinases 1, 2 (SphK1/2) and sphingosine-1-phosphate (S1P) was recently reported in AD. However, the effect of AD-related amyloid beta (...

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Detalles Bibliográficos
Autores principales:	Gassowska, Magdalena, Cieslik, Magdalena, Wilkaniec, Anna, Strosznajder, Joanna B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2014
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962740/ https://www.ncbi.nlm.nih.gov/pubmed/24452756 http://dx.doi.org/10.1007/s11064-014-1240-3

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