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Prolyl-hydroxylase 3: evolving roles for an ancient signaling protein

The ability of cells to sense oxygen is a highly evolved process that facilitates adaptations to the local oxygen environment and is critical to energy homeostasis. In vertebrates, this process is largely controlled by three intracellular prolyl-4-hydroxylases (PHD) 1–3. These related enzymes share...

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Detalles Bibliográficos
Autores principales: Place, Trenton L, Domann, Frederick E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963164/
https://www.ncbi.nlm.nih.gov/pubmed/24672806
http://dx.doi.org/10.2147/HP.S50091