Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

African trypanosomes are lethal human and animal parasites that use antigenic variation for evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate approximately one third of their nuclear genome, including many minichromosomes, and possibly all sub-telomeres, to...

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Detalles Bibliográficos
Autores principales: Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963442/
https://www.ncbi.nlm.nih.gov/pubmed/24047558
http://dx.doi.org/10.1111/cmi.12215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963442/
https://www.ncbi.nlm.nih.gov/pubmed/24047558
http://dx.doi.org/10.1111/cmi.12215

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