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Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control
African trypanosomes are lethal human and animal parasites that use antigenic variation for evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate approximately one third of their nuclear genome, including many minichromosomes, and possibly all sub-telomeres, to...
Autores principales: | Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963442/ https://www.ncbi.nlm.nih.gov/pubmed/24047558 http://dx.doi.org/10.1111/cmi.12215 |
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