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Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying pathogenesis remains elusive. Here, we studied the role...

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Detalles Bibliográficos
Autores principales: Stoop, Esther J M, Mishra, Arun K, Driessen, Nicole N, van Stempvoort, Gunny, Bouchier, Pascale, Verboom, Theo, van Leeuwen, Lisanne M, Sparrius, Marion, Raadsen, Susanne A, van Zon, Maaike, van der Wel, Nicole N, Besra, Gurdyal S, Geurtsen, Jeroen, Bitter, Wilbert, Appelmelk, Ben J, van der Sar, Astrid M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963455/
https://www.ncbi.nlm.nih.gov/pubmed/23902464
http://dx.doi.org/10.1111/cmi.12175