Preferential 8q24 Allelic Imbalance and MYC gene Copy Number in Primary Prostate Cancer

Four independent regions within 8q24 near the MYC gene are associated with risk for prostate cancer. Here we investigated allelic imbalance at 8q24 risk variants and MYC gene DNA copy number (CN) in 27 primary prostate cancers. Heterozygotes were observed in 24 of 27 patients at one or more 8q24 mar...

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Detalles Bibliográficos
Autores principales: Chen, Hankui, Liu, Wanqing, Roberts, Wilmer, Hooker, Stanley, Fedor, Helen, DeMarzo, Angelo, Isaacs, William, Kittles, Rick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963483/
https://www.ncbi.nlm.nih.gov/pubmed/20634801
http://dx.doi.org/10.1038/pcan.2010.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963483/
https://www.ncbi.nlm.nih.gov/pubmed/20634801
http://dx.doi.org/10.1038/pcan.2010.20

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